Systemic sclerosis and the COVID-19 pandemic: World Scleroderma Foundation preliminary advice for patient management.
Identifieur interne : 000524 ( Main/Exploration ); précédent : 000523; suivant : 000525Systemic sclerosis and the COVID-19 pandemic: World Scleroderma Foundation preliminary advice for patient management.
Auteurs : Marco Matucci-Cerinic [Italie] ; Cosimo Bruni [Italie] ; Yannick Allanore [France] ; Massimo Clementi [Italie] ; Lorenzo Dagna [Italie] ; Nemanja S. Damjanov [Serbie] ; Amato De Paulis [Italie] ; Christopher P. Denton [Royaume-Uni] ; Oliver Distler [Suisse] ; David Fox [États-Unis] ; Daniel E. Furst [Italie, États-Unis] ; Dinesh Khanna [États-Unis] ; Thomas Krieg [Allemagne] ; Masataka Kuwana [Japon] ; Eun Bong Lee [Corée du Sud] ; Mengtao Li [République populaire de Chine] ; Shiv Pillai [États-Unis] ; Yukai Wang [République populaire de Chine] ; Xiaofeng Zeng [République populaire de Chine] ; Gloria Taliani [Italie]Source :
- Annals of the rheumatic diseases [ 1468-2060 ] ; 2020.
Descripteurs français
- KwdFr :
- Anticorps monoclonaux humanisés (usage thérapeutique), Betacoronavirus (MeSH), Humains (MeSH), Immunosuppresseurs (administration et posologie), Immunosuppresseurs (effets indésirables), Infections à coronavirus (physiopathologie), Infections à coronavirus (traitement médicamenteux), Infections à coronavirus (épidémiologie), Pandémies (MeSH), Pneumopathie virale (physiopathologie), Pneumopathie virale (traitement médicamenteux), Pneumopathie virale (virologie), Pneumopathie virale (épidémiologie), Pneumopathies interstitielles (immunologie), Pneumopathies interstitielles (virologie), Sclérodermie systémique (immunologie), Sclérodermie systémique (thérapie), Sclérodermie systémique (virologie), Sclérodermie systémique (épidémiologie), Syndrome de détresse respiratoire de l'adulte (traitement médicamenteux), Syndrome de détresse respiratoire de l'adulte (virologie).
- MESH :
- administration et posologie : Immunosuppresseurs.
- effets indésirables : Immunosuppresseurs.
- immunologie : Pneumopathies interstitielles, Sclérodermie systémique.
- physiopathologie : Infections à coronavirus, Pneumopathie virale.
- thérapie : Sclérodermie systémique.
- traitement médicamenteux : Infections à coronavirus, Pneumopathie virale, Syndrome de détresse respiratoire de l'adulte.
- usage thérapeutique : Anticorps monoclonaux humanisés.
- virologie : Pneumopathie virale, Pneumopathies interstitielles, Sclérodermie systémique, Syndrome de détresse respiratoire de l'adulte.
- épidémiologie : Infections à coronavirus, Pneumopathie virale, Sclérodermie systémique.
- Betacoronavirus, Humains, Pandémies.
English descriptors
- KwdEn :
- Antibodies, Monoclonal, Humanized (therapeutic use), Betacoronavirus (MeSH), Coronavirus Infections (drug therapy), Coronavirus Infections (epidemiology), Coronavirus Infections (physiopathology), Humans (MeSH), Immunosuppressive Agents (administration & dosage), Immunosuppressive Agents (adverse effects), Lung Diseases, Interstitial (immunology), Lung Diseases, Interstitial (virology), Pandemics (MeSH), Pneumonia, Viral (drug therapy), Pneumonia, Viral (epidemiology), Pneumonia, Viral (physiopathology), Pneumonia, Viral (virology), Respiratory Distress Syndrome, Adult (drug therapy), Respiratory Distress Syndrome, Adult (virology), Scleroderma, Systemic (epidemiology), Scleroderma, Systemic (immunology), Scleroderma, Systemic (therapy), Scleroderma, Systemic (virology).
- MESH :
- chemical , administration & dosage : Immunosuppressive Agents.
- chemical , adverse effects : Immunosuppressive Agents.
- chemical , therapeutic use : Antibodies, Monoclonal, Humanized.
- drug therapy : Coronavirus Infections, Pneumonia, Viral, Respiratory Distress Syndrome, Adult.
- epidemiology : Coronavirus Infections, Pneumonia, Viral, Scleroderma, Systemic.
- immunology : Lung Diseases, Interstitial, Scleroderma, Systemic.
- physiopathology : Coronavirus Infections, Pneumonia, Viral.
- therapy : Scleroderma, Systemic.
- virology : Lung Diseases, Interstitial, Pneumonia, Viral, Respiratory Distress Syndrome, Adult, Scleroderma, Systemic.
- Betacoronavirus, Humans, Pandemics.
Abstract
Due to the frequent presence of interstitial lung disease and widespread use of immunosuppressive treatment, systemic sclerosis (SSc) patients may be considered at risk for a more severe disease course and higher mortality when they develop Severe Acute Respiratory Syndrome - Coronavirus - 2 (SARS-CoV-2) virus infection. Therefore, with World Scleroderma Foundation endorsement, experts from different specialties including rheumatology, virology and clinical immunology gathered virtually to answer to the main practical clinical questions regarding SARS-CoV-2 infection coming from both patients and physicians. This preliminary advice is aligned with other national and international recommendations, adapted for SSc patients.
DOI: 10.1136/annrheumdis-2020-217407
PubMed: 32349982
Affiliations:
- Allemagne, Corée du Sud, France, Italie, Japon, Royaume-Uni, République populaire de Chine, Serbie, Suisse, États-Unis
- Angleterre, Californie, District de Columbia, Grand Londres, Lombardie, Massachusetts, Michigan, Région capitale de Séoul, Région de Kantō, Île-de-France
- Londres, Milan, Paris, Pékin, Séoul, Tokyo, Washington (district de Columbia)
- University College de Londres, Université de Washington
Links toward previous steps (curation, corpus...)
Le document en format XML
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Damjanov</name><affiliation wicri:level="1"><nlm:affiliation>Rheumatology department, University of Belgrade School of Medicine, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Rheumatology department, University of Belgrade School of Medicine, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="De Paulis, Amato" sort="De Paulis, Amato" uniqKey="De Paulis A" first="Amato" last="De Paulis">Amato De Paulis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Denton, Christopher P" sort="Denton, Christopher P" uniqKey="Denton C" first="Christopher P" last="Denton">Christopher P. Denton</name><affiliation wicri:level="4"><nlm:affiliation>Department of Rheumatology, Royal Free Hospital, University College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Rheumatology, Royal Free Hospital, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Distler, Oliver" sort="Distler, Oliver" uniqKey="Distler O" first="Oliver" last="Distler">Oliver Distler</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Rheumatology, University Hospital Zurich, Zurich</wicri:regionArea><wicri:noRegion>Zurich</wicri:noRegion></affiliation></author><author><name sortKey="Fox, David" sort="Fox, David" uniqKey="Fox D" first="David" last="Fox">David Fox</name><affiliation wicri:level="2"><nlm:affiliation>Rheumatology department, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rheumatology department, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Furst, Daniel E" sort="Furst, Daniel E" uniqKey="Furst D" first="Daniel E" last="Furst">Daniel E. Furst</name><affiliation wicri:level="1"><nlm:affiliation>Department of Experimental and Clinical Medicine, Division of Rheumatology, Università degli Studi di Firenze, Firenze, Toscana, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental and Clinical Medicine, Division of Rheumatology, Università degli Studi di Firenze, Firenze, Toscana</wicri:regionArea><wicri:noRegion>Toscana</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Division of Rheumatology, University of California at Los Angeles, Los Angeles, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Division of Rheumatology, University of California at Los Angeles, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>University of Washington, Seattle, Washington DC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Washington, Seattle, Washington DC</wicri:regionArea><placeName><settlement type="city">Washington (district de Columbia)</settlement><region type="state">District de Columbia</region></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Khanna, Dinesh" sort="Khanna, Dinesh" uniqKey="Khanna D" first="Dinesh" last="Khanna">Dinesh Khanna</name><affiliation wicri:level="2"><nlm:affiliation>Rheumatology department, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rheumatology department, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Krieg, Thomas" sort="Krieg, Thomas" uniqKey="Krieg T" first="Thomas" last="Krieg">Thomas Krieg</name><affiliation wicri:level="1"><nlm:affiliation>Translational Matrix Biology, Medical Faculty, Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Translational Matrix Biology, Medical Faculty, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Kuwana, Masataka" sort="Kuwana, Masataka" uniqKey="Kuwana M" first="Masataka" last="Kuwana">Masataka Kuwana</name><affiliation wicri:level="3"><nlm:affiliation>Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Lee, Eun Bong" sort="Lee, Eun Bong" uniqKey="Lee E" first="Eun Bong" last="Lee">Eun Bong Lee</name><affiliation wicri:level="3"><nlm:affiliation>Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Internal Medicine, Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Li, Mengtao" sort="Li, Mengtao" uniqKey="Li M" first="Mengtao" last="Li">Mengtao Li</name><affiliation wicri:level="3"><nlm:affiliation>Rheumatology & Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Rheumatology & Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Pillai, Shiv" sort="Pillai, Shiv" uniqKey="Pillai S" first="Shiv" last="Pillai">Shiv Pillai</name><affiliation wicri:level="2"><nlm:affiliation>Ragon Institute, Massachusetts General Hospital, Cambridge, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Ragon Institute, Massachusetts General Hospital, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Wang, Yukai" sort="Wang, Yukai" uniqKey="Wang Y" first="Yukai" last="Wang">Yukai Wang</name><affiliation wicri:level="1"><nlm:affiliation>Rheumatology department, Shantou Central Hospital, Shantou, Guangdong, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Rheumatology department, Shantou Central Hospital, Shantou, Guangdong</wicri:regionArea><wicri:noRegion>Guangdong</wicri:noRegion></affiliation></author><author><name sortKey="Zeng, Xiaofeng" sort="Zeng, Xiaofeng" uniqKey="Zeng X" first="Xiaofeng" last="Zeng">Xiaofeng Zeng</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Taliani, Gloria" sort="Taliani, Gloria" uniqKey="Taliani G" first="Gloria" last="Taliani">Gloria Taliani</name><affiliation wicri:level="1"><nlm:affiliation>Infectious Diseases Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Roma, Lazio, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Infectious Diseases Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Roma, Lazio</wicri:regionArea><wicri:noRegion>Lazio</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32349982</idno><idno type="pmid">32349982</idno><idno type="doi">10.1136/annrheumdis-2020-217407</idno><idno type="wicri:Area/Main/Corpus">001529</idno><idno 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Division of Rheumatology, Università degli Studi di Firenze, Firenze, Toscana</wicri:regionArea><wicri:noRegion>Toscana</wicri:noRegion></affiliation></author><author><name sortKey="Bruni, Cosimo" sort="Bruni, Cosimo" uniqKey="Bruni C" first="Cosimo" last="Bruni">Cosimo Bruni</name><affiliation wicri:level="1"><nlm:affiliation>Department of Experimental and Clinical Medicine, Division of Rheumatology, Università degli Studi di Firenze, Firenze, Toscana, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental and Clinical Medicine, Division of Rheumatology, Università degli Studi di Firenze, Firenze, Toscana</wicri:regionArea><wicri:noRegion>Toscana</wicri:noRegion></affiliation></author><author><name sortKey="Allanore, Yannick" sort="Allanore, Yannick" uniqKey="Allanore Y" first="Yannick" last="Allanore">Yannick Allanore</name><affiliation wicri:level="3"><nlm:affiliation>Rheumatology Department, Cochin Hospital, APHP, Paris Descartes University, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Rheumatology Department, Cochin Hospital, APHP, Paris Descartes University, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Clementi, Massimo" sort="Clementi, Massimo" uniqKey="Clementi M" first="Massimo" last="Clementi">Massimo Clementi</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Microbiology and Virology, San Raffaele Hospital, Milano, Lombardia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Microbiology and Virology, San Raffaele Hospital, Milano, Lombardia</wicri:regionArea><wicri:noRegion>Lombardia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Unit of Microbiology and Virology, Università Vita Salute San Raffaele, Milano, Lombardia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Microbiology and Virology, Università Vita Salute San Raffaele, Milano, Lombardia</wicri:regionArea><wicri:noRegion>Lombardia</wicri:noRegion></affiliation></author><author><name sortKey="Dagna, Lorenzo" sort="Dagna, Lorenzo" uniqKey="Dagna L" first="Lorenzo" last="Dagna">Lorenzo Dagna</name><affiliation wicri:level="3"><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Vita-Salute San Raffaele University, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Damjanov, Nemanja S" sort="Damjanov, Nemanja S" uniqKey="Damjanov N" first="Nemanja S" last="Damjanov">Nemanja S. Damjanov</name><affiliation wicri:level="1"><nlm:affiliation>Rheumatology department, University of Belgrade School of Medicine, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Rheumatology department, University of Belgrade School of Medicine, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="De Paulis, Amato" sort="De Paulis, Amato" uniqKey="De Paulis A" first="Amato" last="De Paulis">Amato De Paulis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Denton, Christopher P" sort="Denton, Christopher P" uniqKey="Denton C" first="Christopher P" last="Denton">Christopher P. Denton</name><affiliation wicri:level="4"><nlm:affiliation>Department of Rheumatology, Royal Free Hospital, University College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Rheumatology, Royal Free Hospital, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Distler, Oliver" sort="Distler, Oliver" uniqKey="Distler O" first="Oliver" last="Distler">Oliver Distler</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Rheumatology, University Hospital Zurich, Zurich</wicri:regionArea><wicri:noRegion>Zurich</wicri:noRegion></affiliation></author><author><name sortKey="Fox, David" sort="Fox, David" uniqKey="Fox D" first="David" last="Fox">David Fox</name><affiliation wicri:level="2"><nlm:affiliation>Rheumatology department, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rheumatology department, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Furst, Daniel E" sort="Furst, Daniel E" uniqKey="Furst D" first="Daniel E" last="Furst">Daniel E. Furst</name><affiliation wicri:level="1"><nlm:affiliation>Department of Experimental and Clinical Medicine, Division of Rheumatology, Università degli Studi di Firenze, Firenze, Toscana, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental and Clinical Medicine, Division of Rheumatology, Università degli Studi di Firenze, Firenze, Toscana</wicri:regionArea><wicri:noRegion>Toscana</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Division of Rheumatology, University of California at Los Angeles, Los Angeles, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Division of Rheumatology, University of California at Los Angeles, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>University of Washington, Seattle, Washington DC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Washington, Seattle, Washington DC</wicri:regionArea><placeName><settlement type="city">Washington (district de Columbia)</settlement><region type="state">District de Columbia</region></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Khanna, Dinesh" sort="Khanna, Dinesh" uniqKey="Khanna D" first="Dinesh" last="Khanna">Dinesh Khanna</name><affiliation wicri:level="2"><nlm:affiliation>Rheumatology department, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rheumatology department, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Krieg, Thomas" sort="Krieg, Thomas" uniqKey="Krieg T" first="Thomas" last="Krieg">Thomas Krieg</name><affiliation wicri:level="1"><nlm:affiliation>Translational Matrix Biology, Medical Faculty, Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Translational Matrix Biology, Medical Faculty, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Kuwana, Masataka" sort="Kuwana, Masataka" uniqKey="Kuwana M" first="Masataka" last="Kuwana">Masataka Kuwana</name><affiliation wicri:level="3"><nlm:affiliation>Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Lee, Eun Bong" sort="Lee, Eun Bong" uniqKey="Lee E" first="Eun Bong" last="Lee">Eun Bong Lee</name><affiliation wicri:level="3"><nlm:affiliation>Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Internal Medicine, Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Li, Mengtao" sort="Li, Mengtao" uniqKey="Li M" first="Mengtao" last="Li">Mengtao Li</name><affiliation wicri:level="3"><nlm:affiliation>Rheumatology & Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Rheumatology & Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Pillai, Shiv" sort="Pillai, Shiv" uniqKey="Pillai S" first="Shiv" last="Pillai">Shiv Pillai</name><affiliation wicri:level="2"><nlm:affiliation>Ragon Institute, Massachusetts General Hospital, Cambridge, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Ragon Institute, Massachusetts General Hospital, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Wang, Yukai" sort="Wang, Yukai" uniqKey="Wang Y" first="Yukai" last="Wang">Yukai Wang</name><affiliation wicri:level="1"><nlm:affiliation>Rheumatology department, Shantou Central Hospital, Shantou, Guangdong, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Rheumatology department, Shantou Central Hospital, Shantou, Guangdong</wicri:regionArea><wicri:noRegion>Guangdong</wicri:noRegion></affiliation></author><author><name sortKey="Zeng, Xiaofeng" sort="Zeng, Xiaofeng" uniqKey="Zeng X" first="Xiaofeng" last="Zeng">Xiaofeng Zeng</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Taliani, Gloria" sort="Taliani, Gloria" uniqKey="Taliani G" first="Gloria" last="Taliani">Gloria Taliani</name><affiliation wicri:level="1"><nlm:affiliation>Infectious Diseases Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Roma, Lazio, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Infectious Diseases Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Roma, Lazio</wicri:regionArea><wicri:noRegion>Lazio</wicri:noRegion></affiliation></author></analytic><series><title level="j">Annals of the rheumatic diseases</title><idno type="eISSN">1468-2060</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibodies, Monoclonal, Humanized (therapeutic use)</term><term>Betacoronavirus (MeSH)</term><term>Coronavirus Infections (drug therapy)</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (physiopathology)</term><term>Humans (MeSH)</term><term>Immunosuppressive Agents (administration & dosage)</term><term>Immunosuppressive Agents (adverse effects)</term><term>Lung Diseases, Interstitial (immunology)</term><term>Lung Diseases, Interstitial (virology)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (drug therapy)</term><term>Pneumonia, Viral (epidemiology)</term><term>Pneumonia, Viral (physiopathology)</term><term>Pneumonia, Viral (virology)</term><term>Respiratory Distress Syndrome, Adult (drug therapy)</term><term>Respiratory Distress Syndrome, Adult (virology)</term><term>Scleroderma, Systemic (epidemiology)</term><term>Scleroderma, Systemic (immunology)</term><term>Scleroderma, Systemic (therapy)</term><term>Scleroderma, Systemic (virology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Anticorps monoclonaux humanisés (usage thérapeutique)</term><term>Betacoronavirus (MeSH)</term><term>Humains (MeSH)</term><term>Immunosuppresseurs (administration et posologie)</term><term>Immunosuppresseurs (effets indésirables)</term><term>Infections à coronavirus (physiopathologie)</term><term>Infections à coronavirus (traitement médicamenteux)</term><term>Infections à coronavirus (épidémiologie)</term><term>Pandémies (MeSH)</term><term>Pneumopathie virale (physiopathologie)</term><term>Pneumopathie virale (traitement médicamenteux)</term><term>Pneumopathie virale (virologie)</term><term>Pneumopathie virale (épidémiologie)</term><term>Pneumopathies interstitielles (immunologie)</term><term>Pneumopathies interstitielles (virologie)</term><term>Sclérodermie systémique (immunologie)</term><term>Sclérodermie systémique (thérapie)</term><term>Sclérodermie systémique (virologie)</term><term>Sclérodermie systémique (épidémiologie)</term><term>Syndrome de détresse respiratoire de l'adulte (traitement médicamenteux)</term><term>Syndrome de détresse respiratoire de l'adulte (virologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Immunosuppressive Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Immunosuppressive Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antibodies, Monoclonal, Humanized</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Immunosuppresseurs</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term><term>Respiratory Distress Syndrome, Adult</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Immunosuppresseurs</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term><term>Scleroderma, Systemic</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Pneumopathies interstitielles</term><term>Sclérodermie systémique</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Lung Diseases, Interstitial</term><term>Scleroderma, Systemic</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Scleroderma, Systemic</term></keywords><keywords scheme="MESH" qualifier="thérapie" xml:lang="fr"><term>Sclérodermie systémique</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term><term>Syndrome de détresse respiratoire de l'adulte</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Anticorps monoclonaux humanisés</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Pneumopathie virale</term><term>Pneumopathies interstitielles</term><term>Sclérodermie systémique</term><term>Syndrome de détresse respiratoire de l'adulte</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Lung Diseases, Interstitial</term><term>Pneumonia, Viral</term><term>Respiratory Distress Syndrome, Adult</term><term>Scleroderma, Systemic</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term><term>Sclérodermie systémique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Betacoronavirus</term><term>Humans</term><term>Pandemics</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Betacoronavirus</term><term>Humains</term><term>Pandémies</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Due to the frequent presence of interstitial lung disease and widespread use of immunosuppressive treatment, systemic sclerosis (SSc) patients may be considered at risk for a more severe disease course and higher mortality when they develop Severe Acute Respiratory Syndrome - Coronavirus - 2 (SARS-CoV-2) virus infection. Therefore, with World Scleroderma Foundation endorsement, experts from different specialties including rheumatology, virology and clinical immunology gathered virtually to answer to the main practical clinical questions regarding SARS-CoV-2 infection coming from both patients and physicians. This preliminary advice is aligned with other national and international recommendations, adapted for SSc patients.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32349982</PMID><DateCompleted><Year>2020</Year><Month>05</Month><Day>22</Day></DateCompleted><DateRevised><Year>2020</Year><Month>05</Month><Day>22</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1468-2060</ISSN><JournalIssue CitedMedium="Internet"><Volume>79</Volume><Issue>6</Issue><PubDate><Year>2020</Year><Month>06</Month></PubDate></JournalIssue><Title>Annals of the rheumatic diseases</Title><ISOAbbreviation>Ann. Rheum. Dis.</ISOAbbreviation></Journal><ArticleTitle>Systemic sclerosis and the COVID-19 pandemic: World Scleroderma Foundation preliminary advice for patient management.</ArticleTitle><Pagination><MedlinePgn>724-726</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1136/annrheumdis-2020-217407</ELocationID><Abstract><AbstractText>Due to the frequent presence of interstitial lung disease and widespread use of immunosuppressive treatment, systemic sclerosis (SSc) patients may be considered at risk for a more severe disease course and higher mortality when they develop Severe Acute Respiratory Syndrome - Coronavirus - 2 (SARS-CoV-2) virus infection. Therefore, with World Scleroderma Foundation endorsement, experts from different specialties including rheumatology, virology and clinical immunology gathered virtually to answer to the main practical clinical questions regarding SARS-CoV-2 infection coming from both patients and physicians. This preliminary advice is aligned with other national and international recommendations, adapted for SSc patients.</AbstractText><CopyrightInformation>© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y" EqualContrib="Y"><LastName>Matucci-Cerinic</LastName><ForeName>Marco</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Experimental and Clinical Medicine, Division of Rheumatology, Università degli Studi di Firenze, Firenze, Toscana, Italy marco.matuccicerinic@unifi.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y" EqualContrib="Y"><LastName>Bruni</LastName><ForeName>Cosimo</ForeName><Initials>C</Initials><Identifier Source="ORCID">0000-0003-2813-2083</Identifier><AffiliationInfo><Affiliation>Department of Experimental and Clinical Medicine, Division of Rheumatology, Università degli Studi di Firenze, Firenze, Toscana, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Allanore</LastName><ForeName>Yannick</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Rheumatology Department, Cochin Hospital, APHP, Paris Descartes University, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Clementi</LastName><ForeName>Massimo</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Unit of Microbiology and Virology, San Raffaele Hospital, Milano, Lombardia, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Unit of Microbiology and Virology, Università Vita Salute San Raffaele, Milano, Lombardia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dagna</LastName><ForeName>Lorenzo</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Vita-Salute San Raffaele University, Milan, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Damjanov</LastName><ForeName>Nemanja S</ForeName><Initials>NS</Initials><AffiliationInfo><Affiliation>Rheumatology department, University of Belgrade School of Medicine, Belgrade, Serbia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Paulis</LastName><ForeName>Amato</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Translational Medical Sciences and Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Naples, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Denton</LastName><ForeName>Christopher P</ForeName><Initials>CP</Initials><Identifier Source="ORCID">0000-0003-3975-8938</Identifier><AffiliationInfo><Affiliation>Department of Rheumatology, Royal Free Hospital, University College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Distler</LastName><ForeName>Oliver</ForeName><Initials>O</Initials><Identifier Source="ORCID">0000-0002-0546-8310</Identifier><AffiliationInfo><Affiliation>Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fox</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Rheumatology department, University of Michigan, Ann Arbor, Michigan, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Furst</LastName><ForeName>Daniel E</ForeName><Initials>DE</Initials><AffiliationInfo><Affiliation>Department of Experimental and Clinical Medicine, Division of Rheumatology, Università degli Studi di Firenze, Firenze, Toscana, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medicine, Division of Rheumatology, University of California at Los Angeles, Los Angeles, California, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Washington, Seattle, Washington DC, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Khanna</LastName><ForeName>Dinesh</ForeName><Initials>D</Initials><Identifier Source="ORCID">0000-0003-1412-4453</Identifier><AffiliationInfo><Affiliation>Rheumatology department, University of Michigan, Ann Arbor, Michigan, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Krieg</LastName><ForeName>Thomas</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Translational Matrix Biology, Medical Faculty, Cologne, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kuwana</LastName><ForeName>Masataka</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0001-8352-6136</Identifier><AffiliationInfo><Affiliation>Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>Eun Bong</ForeName><Initials>EB</Initials><Identifier Source="ORCID">0000-0003-0703-1208</Identifier><AffiliationInfo><Affiliation>Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Mengtao</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0003-4252-2889</Identifier><AffiliationInfo><Affiliation>Rheumatology & Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pillai</LastName><ForeName>Shiv</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Ragon Institute, Massachusetts General Hospital, Cambridge, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Yukai</ForeName><Initials>Y</Initials><Identifier Source="ORCID">0000-0003-2468-3208</Identifier><AffiliationInfo><Affiliation>Rheumatology department, Shantou Central Hospital, Shantou, Guangdong, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zeng</LastName><ForeName>Xiaofeng</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Taliani</LastName><ForeName>Gloria</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Infectious Diseases Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Roma, Lazio, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017065">Practice Guideline</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>04</Month><Day>29</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Ann Rheum Dis</MedlineTA><NlmUniqueID>0372355</NlmUniqueID><ISSNLinking>0003-4967</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D061067">Antibodies, Monoclonal, Humanized</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007166">Immunosuppressive Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>I031V2H011</RegistryNumber><NameOfSubstance UI="C502936">tocilizumab</NameOfSubstance></Chemical></ChemicalList><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D061067" MajorTopicYN="N">Antibodies, Monoclonal, Humanized</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007166" MajorTopicYN="N">Immunosuppressive Agents</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017563" MajorTopicYN="N">Lung Diseases, Interstitial</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012128" MajorTopicYN="N">Respiratory Distress Syndrome, Adult</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012595" MajorTopicYN="N">Scleroderma, Systemic</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">autoimmune diseases</Keyword><Keyword MajorTopicYN="Y">hydroxychloroquine</Keyword><Keyword MajorTopicYN="Y">scleroderma</Keyword><Keyword MajorTopicYN="Y">systemic</Keyword></KeywordList><CoiStatement>Competing interests: MMC reports grant and personal fees from Actelion, Biogen, Bayer, Boehringer Ingelheim, CSL Behring, Eli-Lilly, outside the submitted work. CB reports consultancy fee from Actelion, Eli Lilly. YA reports personal fees from Actelion, Bayer, BMS, Boehringer and Curzion, and grants and personal fees from Inventiva, Roche and Sanofi. MC; NSD: none. LD received consultation honoraria from Abbvie, Amgen, Biogen, Bristol-Myers Squibb, Celltrion, Novartis, Pfizer, Roche, Sanofi-Genzyme, and SOBI. CPD has received consultancy fees and/or research grant funding from Actelion, GlaxoSmithKline, Bayer, Sanofi-Aventis, Inventiva, Boehringer Ingelheim, Roche, CSL Behring, UCB Pharma, Leadiant Biosciences, Corbus, Acceleron. OD had consultancy relationship and/or has received research funding from Abbvie, Actelion, Acceleron Pharma, Amgen, AnaMar, Baecon Discovery, Blade Therapeutics, Bayer, Boehringer Ingelheim, Catenion, Competitive Drug Development International Ltd, CSL Behring, Curzion Pharmaceuticals, Ergonex, Galapagos NV, Glenmark Pharmaceuticals GSK, Inventiva, Italfarmaco, iQvia, Lilly, medac, Medscape, Mitsubishi Tanabe Pharma, MSD, Novartis, Pfizer, Roche, Target Bio Science and UCB in the area of potential treatments of scleroderma and its complications. In addition, OD has a patent mir-29 for the treatment of systemic sclerosis issued (US8247389, EP2331143). Grants (2 Jahre) from Actelion, Bayer, Boehringer Ingelheim, Mitsubishi Tanabe Pharma Patent issued: mir-29 for the treatment of systemic sclerosis (US8247389, EP2331143). Comment: To investigate potential treatments of scleroderma and its complications. DF has received consulting fees, speaking fees and/or honoraria from Pfizer and research support from Regeneron, Gilead and Seattle Genetics. DEF: Grant/Research Support Corbus, Galapagos GSK, Pfizer, Talaris, CSL Behring, Mitsubishi; Consultant Actelion, Amgen, Corbus, Galapagos, Novartis, Pfizer, Roche/Genentech, Talaris, CSL Behring, Boehringer Ingelheim; DK reports personal fees from Actelion, Abbvie, Bayer, Boehringer-Ingelheim, Chemomab, Corbus, CSL Behring, Genentech/Roche, Gilead, GSK, Mitsubishi Tanabi, Sanofi-Aventis, UCB Pharma. He reports grants from Bayer, Boehringer-Ingelheim, Genentech/Roche, Pfizer, Sanofi-Aventis and has stock options in Eicos Sciences. MK has received consultancy fees and/or research grant funding from Abbvie, Actelion Pharmaceuticals, Astellas, Bayer, Boehringer Ingelheim, Chugai, Corbus, CSL Behring, Eisai, Mochida, Nippon Shinyaku, Novartis, Ono, Pfizer, Reata and Tanabe-Mitsubishi. SP reports SAB from Abpro. TK recieved consultancy fee and grant funding from Actelion.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>03</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>04</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>04</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>5</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>5</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>5</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32349982</ArticleId><ArticleId IdType="pii">annrheumdis-2020-217407</ArticleId><ArticleId IdType="doi">10.1136/annrheumdis-2020-217407</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Corée du Sud</li><li>France</li><li>Italie</li><li>Japon</li><li>Royaume-Uni</li><li>République populaire de Chine</li><li>Serbie</li><li>Suisse</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Californie</li><li>District de Columbia</li><li>Grand Londres</li><li>Lombardie</li><li>Massachusetts</li><li>Michigan</li><li>Région capitale de Séoul</li><li>Région de Kantō</li><li>Île-de-France</li></region><settlement><li>Londres</li><li>Milan</li><li>Paris</li><li>Pékin</li><li>Séoul</li><li>Tokyo</li><li>Washington (district de Columbia)</li></settlement><orgName><li>University College de Londres</li><li>Université de Washington</li></orgName></list><tree><country name="Italie"><noRegion><name sortKey="Matucci Cerinic, Marco" sort="Matucci Cerinic, Marco" uniqKey="Matucci Cerinic M" first="Marco" last="Matucci-Cerinic">Marco Matucci-Cerinic</name></noRegion><name sortKey="Bruni, Cosimo" sort="Bruni, Cosimo" uniqKey="Bruni C" first="Cosimo" last="Bruni">Cosimo Bruni</name><name sortKey="Clementi, Massimo" sort="Clementi, Massimo" uniqKey="Clementi M" first="Massimo" last="Clementi">Massimo Clementi</name><name sortKey="Clementi, Massimo" sort="Clementi, Massimo" uniqKey="Clementi M" first="Massimo" last="Clementi">Massimo Clementi</name><name sortKey="Dagna, Lorenzo" sort="Dagna, Lorenzo" uniqKey="Dagna L" first="Lorenzo" last="Dagna">Lorenzo Dagna</name><name sortKey="Dagna, Lorenzo" sort="Dagna, Lorenzo" uniqKey="Dagna L" first="Lorenzo" last="Dagna">Lorenzo Dagna</name><name sortKey="De Paulis, Amato" sort="De Paulis, Amato" uniqKey="De Paulis A" first="Amato" last="De Paulis">Amato De Paulis</name><name sortKey="Furst, Daniel E" sort="Furst, Daniel E" uniqKey="Furst D" first="Daniel E" last="Furst">Daniel E. Furst</name><name sortKey="Taliani, Gloria" sort="Taliani, Gloria" uniqKey="Taliani G" first="Gloria" last="Taliani">Gloria Taliani</name></country><country name="France"><region name="Île-de-France"><name sortKey="Allanore, Yannick" sort="Allanore, Yannick" uniqKey="Allanore Y" first="Yannick" last="Allanore">Yannick Allanore</name></region></country><country name="Serbie"><noRegion><name sortKey="Damjanov, Nemanja S" sort="Damjanov, Nemanja S" uniqKey="Damjanov N" first="Nemanja S" last="Damjanov">Nemanja S. Damjanov</name></noRegion></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Denton, Christopher P" sort="Denton, Christopher P" uniqKey="Denton C" first="Christopher P" last="Denton">Christopher P. Denton</name></region></country><country name="Suisse"><noRegion><name sortKey="Distler, Oliver" sort="Distler, Oliver" uniqKey="Distler O" first="Oliver" last="Distler">Oliver Distler</name></noRegion></country><country name="États-Unis"><region name="Michigan"><name sortKey="Fox, David" sort="Fox, David" uniqKey="Fox D" first="David" last="Fox">David Fox</name></region><name sortKey="Furst, Daniel E" sort="Furst, Daniel E" uniqKey="Furst D" first="Daniel E" last="Furst">Daniel E. Furst</name><name sortKey="Furst, Daniel E" sort="Furst, Daniel E" uniqKey="Furst D" first="Daniel E" last="Furst">Daniel E. Furst</name><name sortKey="Khanna, Dinesh" sort="Khanna, Dinesh" uniqKey="Khanna D" first="Dinesh" last="Khanna">Dinesh Khanna</name><name sortKey="Pillai, Shiv" sort="Pillai, Shiv" uniqKey="Pillai S" first="Shiv" last="Pillai">Shiv Pillai</name></country><country name="Allemagne"><noRegion><name sortKey="Krieg, Thomas" sort="Krieg, Thomas" uniqKey="Krieg T" first="Thomas" last="Krieg">Thomas Krieg</name></noRegion></country><country name="Japon"><region name="Région de Kantō"><name sortKey="Kuwana, Masataka" sort="Kuwana, Masataka" uniqKey="Kuwana M" first="Masataka" last="Kuwana">Masataka Kuwana</name></region></country><country name="Corée du Sud"><region name="Région capitale de Séoul"><name sortKey="Lee, Eun Bong" sort="Lee, Eun Bong" uniqKey="Lee E" first="Eun Bong" last="Lee">Eun Bong Lee</name></region></country><country name="République populaire de Chine"><noRegion><name sortKey="Li, Mengtao" sort="Li, Mengtao" uniqKey="Li M" first="Mengtao" last="Li">Mengtao Li</name></noRegion><name sortKey="Wang, Yukai" sort="Wang, Yukai" uniqKey="Wang Y" first="Yukai" last="Wang">Yukai Wang</name><name sortKey="Zeng, Xiaofeng" sort="Zeng, Xiaofeng" uniqKey="Zeng X" first="Xiaofeng" last="Zeng">Xiaofeng Zeng</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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